Yes, you can. You may have a cancer that was not detected at your last breast cancer screening examination, or a new cancer that has developed rapidly since then. At least 1 out of 3 of these cancers will produce symptoms that can lead to detection during the 2 years after a normal screening examination. A breast cancer that is found after a normal screening mammography but before the next screening mammography is called an interval cancer. If you notice changes in your breast that worry you, such as a lump, you should consult your doctor and not wait until your next screening invitation.