Drug typeTumour site (or types) for which there is sufficient evidence of carcinogenicity in humansSites where cancer risk is reduced
Estrogen-only menopausal therapy Endometrium, ovary
Limited evidence: breast

 

Combined estrogen-progestogen menopausal therapy Endometrium (risk decreases with number of days/month of progestogen use), breast  

Combined estrogen-progestogen oral contraceptives

Breast, cervix, liver

Endometrium, ovary

Tamoxifen

Endometrium

Breast