| Drug type | Tumour site (or types) for which there is sufficient evidence of carcinogenicity in humans | Sites where cancer risk is reduced |
|---|---|---|
| Estrogen-only menopausal therapy | Endometrium, ovary Limited evidence: breast |
|
| Combined estrogen-progestogen menopausal therapy | Endometrium (risk decreases with number of days/month of progestogen use), breast | |
|
Combined estrogen-progestogen oral contraceptives |
Breast, cervix, liver |
Endometrium, ovary |
|
Tamoxifen |
Endometrium |
Breast |
